The second installment in the blockbuster Spider-Man movie series (based on the classic Marvel Comics hero) has the web-slinging superhero confronted by a formidable adversary named Dr. Otto Octavius (Alfred Molina), a scientist – better known as "Doc Ock" – whose experiments go awry, mutating him into a metallic, octopus-like creature. Peter must also come to terms with his decision to dedicate his life to fighting crime as Spider-Man or give it all up to finally be with his true love, Mary Jane Watson (Kirsten Dunst), whom he walked away from two years earlier.